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PONG 2.0: allele imputation for the killer cell immunoglobulin-like receptors.

Human molecular genetics - 10 Aug 2026

Sadeeq Suraju A, Leaton Laura A, Kichula Katherine M, Farias Ticiana D J, Font-Porterias Neus, Pollock Nicholas R, Collora Christopher E, Castelli Erick C, Gignoux Christopher R, Norman Paul J

Abstract excerpt

Killer cell immunoglobulin-like receptors (KIRs) are polymorphic immune regulators that modulate natural killer and T cell responses via interactions with human leukocyte antigen (HLA) class I ligands. High combinatorial diversity of KIR and HLA influences infection, autoimmunity, cancer, transplantation, and reproductive success. Although comprehensive KIR genotyping is achievable through targeted sequencing,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to HLA Antigens

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Source

Identifiers

PMID: 42607289
DOI: 10.1093/hmg/ddag075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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