Heterogeneous interactions and polymer entropy decide organization and dynamics of chromatin domains

Abstract excerpt

Chromatin is known to be organized into multiple domains of varying sizes and compaction. While these domains are often imagined as static structures, they are highly dynamic and show cell-to-cell variability. Since processes such as gene regulation and DNA replication occur in the context of these domains, it is important to understand their organization, fluctuation and dynamics. To simulate chromatin domains, o...

Topics

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• Biopolymers
• Chromatin
• Gene Expression Regulation
• Models, Biological
• Mutation

Identifiers and source

Literature Corpus work

cfd6255c-64f3-59b9-ab12-7757ae33ee29

DOI

10.1101/2021.02.17.431616