Article

Dynamic Nucleosome Movement Provides Structural Information of Topological Chromatin Domains in Living Human Cells

2016-06-15

Abstract excerpt

The mammalian genome is organized into submegabase-sized chromatin domains (CDs) including topologically associating domains, which have been identified using chromosome conformation capture-based methods. Single-nucleosome imaging in living mammalian cells has revealed subdiffusively dynamic nucleosome movement. It is unclear how single nucleosomes within CDs fluctuate and how the CD structure reflects the nucleo...

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Literature Corpus work: b43f55b3-4730-5c70-8019-7ce40d0e9bde
DOI: 10.1101/059147

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