Article

Chromatin structure from high resolution microscopy: scaling laws and microphase separation

2023-08-02

Abstract excerpt

Recent advances in experimental fluorescence microscopy allow high accuracy determination (resolution of 50 nm ) of the 3D physical location of multiple (up to ∼ 10 2 ) tagged regions of the chromosome. We investigate publicly available microscopy data for two loci of the human Chr.21 obtained from multiplexed FISH methods for different cell lines and treatments. Inspired by polymer physics models, our analysis...

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Literature Corpus work: 1c299f3c-6453-5dbb-bff3-44a15a65d433
DOI: 10.1101/2023.08.01.551471

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