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Article

Cryo-electron microscopy structure of a nucleosome-bound SWI/SNF chromatin remodeling complex

2019-10-16

Abstract excerpt

The multi-subunit chromatin remodeling complex SWI/SNF 1–3 is highly conserved from yeast to humans and plays critical roles in various cellular processes including transcription and DNA damage repair 4, 5 . It uses the energy from ATP hydrolysis to remodel chromatin structure by sliding and evicting the histone octamer 6–10 , creating DNA regions that become accessible to other essential protein complexes. How...

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Literature Corpus work
c64d66c3-757d-59cd-832e-e68abc877875
DOI
10.1101/805184
Open publication

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Cryo-electron microscopy structure of a nucleosome-bound SWI/SNF chromatin remodeling complexDOI 10.1101/805184
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