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Structure of the nucleosome-bound human BCL7A

31 Mar 2025

Abstract excerpt

Proteins of the BCL7 family (BCL7A, BCL7B, and BCL7C) are among the most recently identified subunits of the mammalian SWI/SNF chromatin remodeler complex and are absent from the unicellular version of this complex. Their function in the complex is unknown, and very limited structural information is available, despite the fact that they are mutated in several cancer types, most notably blood malignancies and...

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PMID: 40207634
DOI: 10.1093/nar/gkaf273

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