Article
The SWI/SNF tumor suppressor complex: Regulation of promoter nucleosomes and beyond.
Nucleus (Austin, Tex.) - 1 Jan 2000
Lu Ping, Roberts Charles W M
Abstract excerpt
Nucleosomes, octamers of histones wrapped in 147 bp of DNA, are the basic unit of chromatin. In eukaryotic cells, the placement of nucleosomes along the genome is highly organized, and modulation of this ordered arrangement contributes to regulation of gene expression. The SWI/SNF complex utilizes the energy of ATP hydrolysis to mobilize nucleosomes and remodel chromatin structure. Recently, the complex has also...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
