Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structure of nucleosome-bound human BAF complex.

Science (New York, N.Y.) - 21 Feb 2020

He Shuang, Wu Zihan, Tian Yuan, Yu Zishuo, Yu Jiali, Wang Xinxin, Li Jie, Liu Bijun, Xu Yanhui

Abstract excerpt

Mammalian SWI/SNF family chromatin remodelers, BRG1/BRM-associated factor (BAF) and polybromo-associated BAF (PBAF), regulate chromatin structure and transcription, and their mutations are linked to cancers. The 3.7-angstrom-resolution cryo-electron microscopy structure of human BAF bound to the nucleosome reveals that the nucleosome is sandwiched by the base and the adenosine triphosphatase (ATPase) modules,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Transcription Factors
Share to Adenosine Triphosphatases
Share to Adenosine Triphosphate

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Hydrolysis

Share to Mutation

Share to Neoplasms

Share to Nuclear Proteins

Source

Identifiers

PMID: 32001526
DOI: 10.1126/science.aaz9761

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structure of nucleosome-bound human BAF complex.PMID 32001526Read ↗

Cryo-electron microscopy structure of a nucleosome-bound SWI/SNF chromatin remodeling complexSemantic proximity Read ↗

The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer.Semantic proximity Read ↗

Structure of the nucleosome-bound human BCL7ASemantic proximity Read ↗

Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomicsSemantic proximity Read ↗

The Molecular Basis of Specific DNA Binding by the BRG1 AT-hook and BromodomainSemantic proximity Read ↗

Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease DevelopmentSemantic proximity Read ↗

Structure of nucleosome-bound human PBAF complexSemantic proximity Read ↗

The molecular basis of selective DNA binding by the BRG1 AT-hook and bromodomain.Semantic proximity Read ↗

Structure of the SWI/SNF complex bound to the nucleosome and insights into the functional modularitySemantic proximity Read ↗

ARID1A regulates histone octamer transfer activity of human canonical BAF complexSemantic proximity Read ↗

Structure of the human Bre1 complex bound to the nucleosomeSemantic proximity Read ↗

BAFfling pathologies: Alterations of BAF complexes in cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.