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Article

Architecture of SWI/SNF chromatin remodeling complex

15 Mar 2018

Abstract excerpt

Dear Editor, The SWI/SNF complex is a large ATP-dependent chromatin remodeling complex that is highly conserved from yeast to human, which is essential for transcription regulation, genomic stability, DNA repair and many aspects of development (Kasten et al., 2011). SWI/SNF contains more than 10 subunits (M.W. >1 MDa), including a DNA-dependent ATPase subunit and several accessory subunits. Mutations in several...

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PMID: 29546678
DOI: 10.1007/s13238-018-0524-9

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