Article
Architecture of the SWI/SNF-nucleosome complex.
Molecular and cellular biology - 1 Oct 2008
Dechassa Mekonnen Lemma, Zhang Bei, Horowitz-Scherer Rachel, Persinger Jim, Woodcock Christopher L, Peterson Craig L, Bartholomew Blaine
Abstract excerpt
The SWI/SNF complex disrupts and mobilizes chromatin in an ATP-dependent manner. SWI/SNF interactions with nucleosomes were mapped by DNA footprinting and site-directed DNA and protein cross-linking when SWI/SNF was recruited by a transcription activator. SWI/SNF was found by DNA footprinting to...
Topics
- Adenosine Triphosphatases
- Animals
- Chromosomal Proteins, Non-Histone
- DNA
- DNA-Binding Proteins
- Histones
- Models, Molecular
- Mutation
- Nucleosomes
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Transcription Factors
- Xenopus laevis