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The Role and Activity of SWI/SNF Chromatin Remodelers

8 Mar 2023

Abstract excerpt

SWITCH deficient SUCROSE NONFERMENTING (SWI/SNF) class chromatin remodeling complexes (CRCs) use the energy derived from ATP hydrolysis to facilitate access of proteins to the genomic DNA for transcription, replication, and DNA repair. Uniquely, SWI/SNF CRCs can both slide the histone octamer along the DNA or eject it from the DNA. Given their ability to change the chromatin status quo, SWI/SNF remodelers are...

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PMID: 36889009
DOI: 10.1146/annurev-arplant-102820-093218

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