Article

A systematic framework for assessing the clinical impact of polygenic risk scores

2020-04-08

Abstract excerpt

<h4>ABSTRACT</h4> Risk prediction models provide empirical recommendations that ultimately aim to deliver optimal patient outcomes. Genetic information, in the form of a polygenic risk score (PRS), may be included in these models to significantly increase their accuracy. Several analyses of PRS accuracy have been completed, nearly all focus on only a few diseases and report limited statistics. This narrow approach...

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Literature Corpus work: c18723a8-bc20-506e-8c55-54d1c0e00910
DOI: 10.1101/2020.04.06.20055574

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