Article

Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC

2022-06-03

Abstract excerpt

The ability to differentiate stem cells into human cell types is essential to define basic mechanisms and therapeutics, especially for cell types not routinely accessible by biopsies. But while engineered expression of transcription factors (TFs) identified through TF screens has been found to rapidly and efficiently produce some cell types, generation of other cell types that require complex combinations of TFs h...

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Literature Corpus work: be9be757-e751-5a87-952f-14169b4020de
DOI: 10.1101/2022.06.03.494617

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