Article

Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration

2023-03-10

Abstract excerpt

<h4>Background</h4> Microglia are the resident immune cells in the brain that play a key role in driving neuroinflammation, a hallmark of neurodegenerative disorders. Inducible microglia-like cells have been developed as an in vitro platform for molecular and therapeutic hypothesis generation and testing. However, there has been no systematic assessment of similarity of these cells to primary human microglia alon...

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Literature Corpus work: 042b3395-afa6-5756-9e47-4cbf59b8de81
DOI: 10.1101/2023.03.09.531934

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