Article
A resource for generating and manipulating human microglial states in vitro
2022-05-02
Abstract excerpt
Microglia have emerged as key players in the pathogenesis of neurodegenerative conditions such as Alzheimer’s disease (AD). In response to CNS stimuli, these cells adopt distinct transcriptional and functional subtypes known as states. However, an understanding of the function of these states has been elusive, especially in human microglia, due to lack of tools to model and manipulate this cell-type. Here, we prov...
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Identifiers and source
- Literature Corpus work
- 3e396554-4ae3-5fab-85eb-35c141749618
- DOI
- 10.1101/2022.05.02.490100