Article

Transcriptional landscape of direct reprogramming toward the hematopoietic lineage

2024-08-26

Abstract excerpt

<h4>SUMMARY</h4> Direct reprogramming of human fibroblasts into hematopoietic stem cells (HSCs) offers a promising strategy for generating autologous cells to treat blood and immune disorders. Current protocols are limited by low efficiency and insufficient tools for evaluating reprogramming outcomes. Although functional assays are the standard for confirming cell identity, they require fully reprogrammed cells,...

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Literature Corpus work: 6ccab6de-6268-5dbb-8605-634378aab1c9
DOI: 10.1101/2024.08.26.609589

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