Article

Multi-omics analysis in primary T cells elucidates mechanisms behind disease associated genetic loci

2023-07-23

Abstract excerpt

<h4>ABSTRACT</h4> In this study, we present the most extensive dataset of chromatin conformation data with matching gene expression and chromatin accessibility from primary T cells to date. We use this data to enhance our understanding of the different mechanisms by which GWAS variants impact gene regulation and revealing how natural genetic variation alter chromatin accessibility and structure in primary cells at...

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Literature Corpus work: bce5a5f1-04a4-5f8b-8b61-100195593b18
DOI: 10.1101/2023.07.19.23292550

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