Article

Methods for detecting co-mutated pathways in cancer samples to inform treatment selection

2016-10-22

Abstract excerpt

Tumor genomes evolve through a selection of mutations. These mutations may complement each other to promote tumorigenesis. To better understand the functional interactions of different processes in cancer, we studied mutation data of a set of tumors and identified significantly co-mutated pathways. Fisher’s exact test is a standard approach that can be used to assess the significance of the joint dysregulation of...

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Literature Corpus work: baa37773-9e42-5870-9b0b-5bbd71241740
DOI: 10.1101/082552

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