Article
Integrated analysis of mutation data from various sources identifies key genes and signaling pathways in hepatocellular carcinoma.
PloS one - 1 Jan 2014
Zhang Yuannv, Qiu Zhaoping, Wei Lin, Tang Ruqi, Lian Baofeng, Zhao Yingjun, He Xianghuo, Xie Lu
Abstract excerpt
BACKGROUND: Recently, a number of studies have performed genome or exome sequencing of hepatocellular carcinoma (HCC) and identified hundreds or even thousands of mutations in protein-coding genes. However, these studies have only focused on a limited number of candidate genes, and many important mutation resources remain to be explored. PRINCIPAL FINDINGS: In this study, we integrated mutation data obtained from...
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