Article
A network of cancer genes with co-occurring and anti-co-occurring mutations.
PloS one - 4 Oct 2010
Cui Qinghua
Abstract excerpt
Certain cancer genes contribute to tumorigenesis in a manner of either co-occurring or mutually exclusive (anti-co-occurring) mutations; however, the global picture of when, where and how these functional interactions occur remains unclear. This study presents a systems biology approach for this purpose. After applying this method to cancer gene mutation data generated from large-scale and whole genome sequencing...
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