Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Shared and unique mutational gene co-occurrences in cancers.

Biochemical and biophysical research communications - 2 Oct 2015

Liu Junqi, Zhao Di, Fan Ruitai

Abstract excerpt

Cancers are often associated with mutations in multiple genes; thus, studying the distributions of genes that harbor cancer-promoting mutations in cancer samples and their co-occurrences could provide insights into cancer diagnostics and treatment. Using data from the Catalogue of Somatic Mutations in Cancer (COSMIC), we found that mutated genes in cancer samples followed a power-law distribution. For instance, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, cdc
Share to Databases, Genetic
Share to DNA Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to Genes, Tumor Suppressor

Share to Models, Genetic

Share to Neoplasms

Share to Oncogenes

Source

Identifiers

PMID: 26315265
DOI: 10.1016/j.bbrc.2015.08.086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Shared and unique mutational gene co-occurrences in cancers.PMID 26315265Read ↗

A network of cancer genes with co-occurring and anti-co-occurring mutations.Semantic proximity Read ↗

Combinatorial patterns of somatic gene mutations in cancer.Semantic proximity Read ↗

Unbiased co-occurring mutational landscapes in tumorigenesisSemantic proximity Read ↗

CoMutDB: the landscape of somatic mutation co-occurrence in cancers.Semantic proximity Read ↗

Evolving patterns of co-mutations from tumor initiation to metastatic progression.Semantic proximity Read ↗

Co-occurrence and mutual exclusivity: what cross-cancer mutation patterns can tell us.Semantic proximity Read ↗

Finding co-mutated genes and candidate cancer genes in cancer genomes by stratified false discovery rate control.Semantic proximity Read ↗

CM-viewer: Visualizing interaction network of co-mutated and mutually exclusively mutated cancer genes.Semantic proximity Read ↗

eTumorRisk, an algorithm predicts cancer risk based on comutated gene networks in an individual’s germline genomeSemantic proximity Read ↗

Analysis of pathway mutation profiles highlights collaboration between cancer-associated superpathways.Semantic proximity Read ↗

Co-occurring Mutations in Different Genes Can Fuel Oncogenic Signaling and Serve as Metastatic Tumor MarkersSemantic proximity Read ↗

Systematic interpretation of comutated genes in large-scale cancer mutation profiles.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.