Article

Co-mutation and exclusion analysis in human tumors, a means for cancer biology studies and treatment design

2017-08-30

Abstract excerpt

<h4>Background</h4> Malignant tumors originate from genomic and epigenomic alterations, which lead to loss of control of the cellular circuitry. These alterations relate with each other in patterns of mutual exclusion and co-occurrence that affect prognosis and treatment response and highlight the need for multitargeted therapy. However, to the best of our knowledge, there are no systematic reports in the literat...

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Literature Corpus work: 2e7d22d7-1090-5150-97f1-701bb807af6d
DOI: 10.1101/182501

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