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Article

CoMutDB: the landscape of somatic mutation co-occurrence in cancers.

Bioinformatics (Oxford, England) - 1 Jan 2023

Jiang Limin, Yu Hui, Tang Jijun, Guo Yan

Abstract excerpt

MOTIVATION: Somatic mutation co-occurrence has been proven to have a profound effect on tumorigenesis. While some studies have been conducted on co-mutations, a centralized resource dedicated to co-mutations in cancer is still lacking. RESULTS: Using multi-omics data from over 30 000 subjects and 1747 cancer cell lines, we present the Cancer co-mutation database (CoMutDB), the most comprehensive resource devoted...

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Identifiers

PMID: 36355452
DOI: 10.1093/bioinformatics/btac725
PMCID: PMC9805589

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