Article

Welch-weighted Egger regression reduces false positives due to correlated pleiotropy in Mendelian randomization

2021-04-10

Abstract excerpt

Modern population-scale biobanks contain simultaneous measurements of many phenotypes, providing unprecedented opportunity to study the relationship between biomarkers and disease. However, inferring causal effects from observational data is notoriously challenging. Mendelian randomization (MR) has recently received increased attention as a class of methods for estimating causal effects using genetic associations....

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Literature Corpus work: b94d9418-0fcd-5280-b803-5392e3860e1e
DOI: 10.1101/2021.04.09.439229

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