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Cancer-myeloid cell invasive program in pediatric-type diffuse high-grade glioma

2026-01-25

Abstract excerpt

<h4>SUMMARY</h4> Pediatric-type diffuse high-grade gliomas (pHGGs) are aggressive, heterogeneous brain tumors shaped by intricate cancer-microenvironment cell-cell interactions. Here, we present an integrative multimodal pHGGmap, encompassing over 800,000 cells from 136 patients profiled across transcriptomic, epigenomic, and spatial modalities. Its analysis delineated robust cancer-myeloid cell programs that str...

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Literature Corpus work
b58911f4-e28c-53eb-a09c-766385c8c6de
DOI
10.64898/2026.01.23.701142
Open publication

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