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A longitudinal single-cell and spatial multiomic atlas of pediatric high-grade glioma

2024-03-08

Abstract excerpt

<h4>Summary</h4> Pediatric high-grade glioma (pHGG) is an incurable central nervous system malignancy that is a leading cause of pediatric cancer death. While pHGG shares many similarities to adult glioma, it is increasingly recognized as a molecularly distinct, yet highly heterogeneous disease. In this study, we longitudinally profiled a molecularly diverse cohort of 16 pHGG patients before and after standard th...

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Literature Corpus work
d719fd72-c1aa-50f0-a5de-1be0f47b6093
DOI
10.1101/2024.03.06.583588
Open publication

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A longitudinal single-cell and spatial multiomic atlas of pediatric high-grade gliomaDOI 10.1101/2024.03.06.583588
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