Article

MrTADFinder: A network modularity based approach to identify topologically associating domains in multiple resolutions

2016-12-29

Abstract excerpt

Genome-wide proximity ligation based assays such as Hi-C have revealed that eukaryotic genomes are organized into structural units called topologically associating domains (TADs). From a visual examination of the chromosomal contact map, however, it is clear that the organization of the domains is not simple or obvious. Instead, TADs exhibit various length scales and, in many cases, a nested arrangement. Here, by...

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Literature Corpus work: af3d7687-38da-5811-a6cc-8eadf5982e03
DOI: 10.1101/097345

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