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DiffGR: Detecting Differentially Interacting Genomic Regions from Hi-C Contact Maps

2020-08-31

Abstract excerpt

Recent advances in Hi-C techniques have allowed us to map genome-wide chromatin interactions and uncover higher-order chromatin structures, thereby shedding light on the principles of genome architecture and functions. However, statistical methods for detecting changes in large-scale chromatin organization such as topologically-associating domains (TADs) are still lacking. We proposed a new statistical method, Dif...

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Literature Corpus work
17b75fda-b1f6-5e8d-b6ab-4f982e430a4a
DOI
10.1101/2020.08.29.273698
Open publication

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DiffGR: Detecting Differentially Interacting Genomic Regions from Hi-C Contact MapsDOI 10.1101/2020.08.29.273698
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