Article

EpiTADformer: A Transformer-Based Model for High-Resolution TAD Boundary Detection Using Epigenomic Signal Embeddings

2026-01-22

Abstract excerpt

The human genome is partitioned at different levels of 3D genome organization, with topologically associating domains (TADs) being among the most well-known and biologically important structures. TAD boundary disruption is associated with a wide range of diseases such as cancer, neurological and developmental disorders. Numerous methods have been developed to detect TAD boundaries from chromatin contact maps obtai...

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Literature Corpus work: 4dcf8b42-eca6-5810-aacc-009cd76e850b
DOI: 10.64898/2026.01.20.700691

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