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A comparative analysis of the immunotranscriptomic features of DENV-1, -3, and -4 human challenge models

2026-02-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Dengue virus (DENV) infections cause a range of clinical symptoms, from a mild febrile illness to severe disease. Higher levels of DENV RNAemia are associated with severe dengue, although this relationship is incompletely understood. Dengue Human Infection Models (DHIMs), in which volunteers are experimentally infected with underattenuated DENV strains, provide an invaluable...

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Literature Corpus work
af1b97be-60ae-5623-8253-d0695c31eff2
DOI
10.64898/2026.02.17.706422
Open publication

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A comparative analysis of the immunotranscriptomic features of DENV-1, -3, and -4 human challenge modelsDOI 10.64898/2026.02.17.706422
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