Article

Virus-inclusive single cell RNA sequencing reveals molecular signature predictive of progression to severe dengue infection

2018-08-09

Abstract excerpt

Dengue virus (DENV) infection can result in severe complications. Yet, the understanding of the molecular correlates of severity is limited, partly due to difficulties in defining the peripheral blood mononuclear cells (PBMCs) that are associated with DENV in vivo. Additionally, there are currently no biomarkers predictive of progression to severe dengue (SD). Bulk transcriptomics data are difficult to interpret b...

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Literature Corpus work: 23a088be-95cb-565b-b3a8-1cc961f3f967
DOI: 10.1101/388181

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