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Temporally integrated single cell RNA sequencing analysis of PBMC from experimental and natural primary human DENV-1 infections

29 Jan 2021

Abstract excerpt

Dengue human infection studies present an opportunity to address many longstanding questions in the field of flavivirus biology. However, limited data are available on how the immunological and transcriptional response elicited by an attenuated challenge virus compares to that associated with a wild-type DENV infection. To determine the kinetic transcriptional signature associated with experimental primary DENV-1...

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PMID: 33513191
DOI: 10.1371/journal.ppat.1009240

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