Article

Temporally integrated single cell RNA sequencing analysis of controlled and natural primary human DENV-1 infections

2020-07-16

Abstract excerpt

Controlled dengue human infection studies present an opportunity to address many longstanding questions in the field of flavivirus biology. However, limited data are available on how the immunological and transcriptional response elicited by an attenuated challenge virus compares to that associated with a wild-type DENV infection. To bridge this knowledge gap, we utilized scRNAseq to analyze PBMC from individuals...

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Literature Corpus work: 58191ded-7cd5-5d28-8cad-e3139471c641
DOI: 10.1101/2020.07.16.206557

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