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Article

Early transcriptional responses after dengue vaccination mirror the response to natural infection and predict neutralizing antibody titers

2018-05-06

Abstract excerpt

<h4>Background: </h4> Several promising live attenuated virus (LAV) dengue vaccines are in development, but information about innate immune responses and early correlates of protection are lacking. <h4>Methods:</h4> We characterized human genome-wide transcripts in whole blood from 10 volunteers at 11 time-points after immunization with the dengue virus type 3 (DENV-3) component of the NIH dengue vaccine candidate...

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Literature Corpus work
ff4689b0-fee4-549b-af49-8d5681a0a1b7
DOI
10.1101/314377
Open publication

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