Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptome-wide changes in gene expression, splicing, and lncRNAs in response to a live attenuated dengue virus vaccine

1 Feb 2022

Abstract excerpt

The tetravalent dengue vaccine candidate, TAK-003, induces a functional antibody response, but the titers of antibodies against the four serotypes of the dengue virus (DENV) can vary. Here, through a transcriptomic analysis on whole blood collected from recipients of a two-dose schedule of TAK-003, we examine gene expression, splicing, and transcript isoform-level changes for both protein-coding and noncoding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to Mosquito-borne diseases and control
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35139383
DOI: 10.1016/j.celrep.2022.110341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptome-wide changes in gene expression, splicing, and lncRNAs in response to a live attenuated dengue virus vaccinePMID 35139383Read ↗

Long Non-Coding RNAs in Response to Ebola Virus Vaccine-Induced ImmunitySemantic proximity Read ↗

Integrative systems vaccinology identification of shared gene signatures between natural dengue infection and vaccination trialsSemantic proximity Read ↗

Early transcriptional responses after dengue vaccination mirror the response to natural infection and predict neutralizing antibody titersSemantic proximity Read ↗

A comparative analysis of the immunotranscriptomic features of DENV-1, -3, and -4 human challenge modelsSemantic proximity Read ↗

Integrated single-cell analysis reveals interferon-driven immune signatures in a DENV1 human infection modelSemantic proximity Read ↗

Global and cell type-specific immunological hallmarks of severe dengue progressionSemantic proximity Read ↗

CD4+ T cells exhibit distinct transcriptional phenotypes in the lymph nodes and blood following mRNA vaccination in humans.Semantic proximity Read ↗

Profiling antibody epitopes induced by mRNA-1273 vaccination and boostersSemantic proximity Read ↗

Immune gene expression analysis indicates the potential of a self-amplifying Covid-19 mRNA vaccineSemantic proximity Read ↗

The Human CD8 <sup>+</sup> T Cell Responses Induced by a Live Attenuated Tetravalent Dengue Vaccine Are Directed against Highly Conserved EpitopesSemantic proximity Read ↗

The Vacc-SeqQC Project: Benchmarking RNA-Seq for Clinical Vaccine StudiesSemantic proximity Read ↗

Variant- and Vaccination-Specific Alternative Splicing Profiles in SARS-CoV-2 InfectionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.