Article

Defining a core configuration for human centromeres during mitosis

2023-05-12

Abstract excerpt

The biorientation of sister chromatids on the mitotic spindle, essential for accurate sister chromatid segregation, relies on critical centromere components including cohesin, the centromere-specific H3 variant CENP-A, and centromeric DNA. Centromeric DNA is highly variable between chromosomes yet must accomplish a similar function. Moreover, how the 50 nm cohesin ring, proposed to encircle sister chromatids, acco...

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Literature Corpus work: a80b8f7d-fa38-5ad9-9797-aab1fcd14e64
DOI: 10.1101/2023.05.10.539634

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