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Heterochromatin boundaries maintain centromere position, size and number

2025-02-05

Abstract excerpt

Centromeres are chromosomal loci that ensure proper chromosome segregation by providing a platform for kinetochore assembly and spindle force transduction during cell division. Human centromeres are defined primarily by a unique chromatin domain featuring the histone H3 variant, Centromere Protein A (CENP-A), that marks a single active centromere locus per chromosome. CENP-A chromatin typically occupies a small su...

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Identifiers and source

Literature Corpus work
9124557a-070e-5c2e-8846-9431a3316c41
DOI
10.1101/2025.02.03.635667
Open publication

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Heterochromatin boundaries maintain centromere position, size and numberDOI 10.1101/2025.02.03.635667
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