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Epigenetic centromere identity is precisely maintained through DNA replication but is uniquely specified among human cells

2022-09-07

Abstract excerpt

Centromere identity is defined and maintained epigenetically by the presence of the histone variant CENP-A. How centromeric CENP-A position is specified and precisely maintained through DNA replication is not fully understood. The recently released Telomere-to-Telomere (T2T-CHM13) genome assembly containing the first complete human centromere sequences provides a new resource for examining CENP-A position. Mapping...

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Identifiers and source

Literature Corpus work
87a5b284-6c65-5167-a617-3bcd5201ee5d
DOI
10.1101/2022.09.07.506974
Open publication

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Epigenetic centromere identity is precisely maintained through DNA replication but is uniquely specified among human cellsDOI 10.1101/2022.09.07.506974
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