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Human centromere formation activates transcription and opens chromatin fibre structure

2021-08-02

Abstract excerpt

Human centromeres appear as constrictions on mitotic chromosomes and form a platform for kinetochore assembly in mitosis. Biophysical experiments led to a suggestion that repetitive DNA at centromeric regions form a compact scaffold necessary for function, but this was revised when neocentromeres were discovered on non-repetitive DNA. To test whether centromeres have a special chromatin structure we have analysed...

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Literature Corpus work
7f1ae331-9e38-545d-ab6a-80a268d22d8a
DOI
10.1101/2021.08.01.454615
Open publication

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Human centromere formation activates transcription and opens chromatin fibre structureDOI 10.1101/2021.08.01.454615
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