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Multidimensional variation and population stratification across 8000 complete human centromeres

2026-07-24

Abstract excerpt

Human centromeres are indispensable for the faithful segregation of chromosomes during cell division, yet their highly repetitive nature has historically precluded comprehensive characterization, leaving fundamental questions about their sequence diversity, evolution trajectories and function dynamics unresolved. Here, we generated 6,312 complete human centromere sequences from 320 phased genome assemblies in Asia...

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Identifiers and source

Literature Corpus work
30291a59-8240-5ab6-bf39-0fe043a1cb4b
DOI
10.64898/2026.07.22.740206
Open publication

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Multidimensional variation and population stratification across 8000 complete human centromeresDOI 10.64898/2026.07.22.740206
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