Article

Complete genomic and epigenetic maps of human centromeres

2021-07-13

Abstract excerpt

Existing human genome assemblies have almost entirely excluded highly repetitive sequences within and near centromeres, limiting our understanding of their sequence, evolution, and essential role in chromosome segregation. Here, we present an extensive study of newly assembled peri/centromeric sequences representing 6.2% (189.9 Mb) of the first complete, telomere-to-telomere human genome assembly (T2T-CHM13). We d...

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Literature Corpus work: 5d03ef1b-e992-5c62-b149-a94de1263b13
DOI: 10.1101/2021.07.12.452052

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