Article

Genetic Substrates of Brain Vulnerability and Resilience in Aging APOE2 Mice

2022-12-13

Abstract excerpt

Understanding the interplay between genotype, age, and sex has potential to reveal factors that determine the switch between successful and pathological aging. APOE allelic variation modulate brain vulnerability and cognitive resilience during aging and Alzheimer disease (AD). The APOE4 allele confers the most risk and has been extensively studied with respect to the control APOE3 allele. The APOE2 allele has been...

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Literature Corpus work: 9dba1daf-1af6-501b-b5f2-a031d9a4841a
DOI: 10.1101/2022.12.12.520146

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