Article

APOE, Immune Factors, Sex, and Diet Interact to Shape Brain Networks in Mouse Models of Aging

2023-10-06

Abstract excerpt

Alzheimer’s disease (AD) presents complex challenges due to its multifactorial nature, poorly understood etiology, and late detection. The mechanisms through which genetic, fixed and modifiable risk factors influence susceptibility to AD are under intense investigation, yet the impact of unique risk factors on brain networks is difficult to disentangle, and their interactions remain unclear. To model multiple risk...

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Literature Corpus work: db47f870-2dd3-57f7-b11f-489e96e094fa
DOI: 10.1101/2023.10.04.560954

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