A novel <i>ISG15</i> transcript restricts influenza A virus infection

Abstract excerpt

<h4>SUMMARY</h4> The interferon response orchestrates antiviral defense through the induction of interferon-stimulated genes (ISGs). Although nearly all human genes undergo alternative splicing, the identity and function of many ISG transcript isoforms remains poorly understood. Using long-read RNA sequencing of human cells that were undergoing an interferon response, we identified a previously unrecognized inter...

Topics

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• Cell Adhesion Molecules Research
• Cytokine Signaling Pathways and Interactions
• Immune Cell Function and Interaction
• Immunotherapy and Immune Responses
• Influenza Virus Research Studies
• interferon and immune responses
• RNA regulation and disease
• Systemic Lupus Erythematosus Research

Identifiers and source

Literature Corpus work

9d5988b7-d7ec-55f9-84f9-e77f5e90a7ad

DOI

10.64898/2026.01.15.699784