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ISG15 driven cellular responses to virus infection

23 Nov 2022

Abstract excerpt

One of the hallmarks of antiviral responses to infection is the production of interferons and subsequently of interferon stimulated genes. Interferon stimulated gene 15 (ISG15) is among the earliest and most abundant proteins induced upon interferon signalling, encompassing versatile functions in host immunity. ISG15 is a ubiquitin like modifier that can be conjugated to substrates in a process analogous to...

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PMID: 36416643
DOI: 10.1042/bst20220839

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