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Article

Transcriptome Regulation by PARP13 in Basal and Antiviral States in Human Cells

2022-12-19

Abstract excerpt

<h4>Summary</h4> The RNA-binding protein PARP13 is a primary factor in the innate antiviral response. PARP13 suppresses translation and drives decay of bound viral and host RNA. PARP13 interacts with many proteins encoded by interferon-stimulated genes (ISG) to activate antiviral pathways including post-translational addition of ISG15, or ISGylation. We performed enhanced crosslinking immunoprecipitation (eCLIP)...

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Identifiers and source

Literature Corpus work
9e1b70a2-6c02-5514-aece-824d9cc0c5a6
DOI
10.1101/2022.12.19.520435
Open publication

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Transcriptome Regulation by PARP13 in Basal and Antiviral States in Human CellsDOI 10.1101/2022.12.19.520435
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