Article

Single-allele chromatin folding is organized by recurrent motifs that are reweighted across cell types and states

2024-09-19

Abstract excerpt

Chromatin folding exhibits extensive cell-to-cell variability, yet whether this variability is dominated by continuously varying conformations or by recurrent organizational patterns remains unclear. Here, we combined high-resolution chromatin tracing with a novel machine learning algorithm to show that chromatin organization can be compactly represented by a limited repertoire of recurrent folding motifs. Using p...

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Literature Corpus work: 9bb2dfb5-9200-5545-938b-b40d3772b97c
DOI: 10.1101/2024.09.18.613689

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