Article

Learning sequence-based regulatory dynamics in single-cell genomics

2024-08-08

Abstract excerpt

Epigenomics assays, such as chromatin accessibility, can identify DNA-sequence-specific regulatory factors. Models that predict read counts from sequence features can explain cell-based readouts using specific DNA patterns (genomic motifs) but do not encode the changes in genomic regulation over time, which is crucial for understanding biological events during cell transitions. To bridge this gap, we present muBi...

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Literature Corpus work: 050a417f-1da4-55d3-8874-0d90a7418c78
DOI: 10.1101/2024.08.07.605876

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