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ChromPolymerDB: A High-Resolution Database of Single-Cell 3D Chromatin Structures for Functional Genomics

2025-09-29

Abstract excerpt

<h4>ABSTRACT</h4> The three-dimensional (3D) organization of chromatin plays a critical role in regulating gene expression and genomic processes like DNA replication, repair, and genome stability. Although these processes occur at the individual-cell level, most chromatin structure data are derived from population-averaged assays, such as Hi-C, obscuring the heterogeneity of single-cell conformations. To address...

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Literature Corpus work: 13e88825-9589-586e-ba3a-0540d3b8617c
DOI: 10.1101/2025.09.27.678816

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