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H3K37me1 couples transcription with DNA replication origin selection

2026-06-23

Abstract excerpt

<h4>Summary</h4> DNA replication initiation in higher eukaryotes occurs at thousands of sites distributed throughout the genome and follows a defined temporal program. However, replication origins are not determined by a conserved DNA motif, and how specific genomic regions are selected for initiation remains poorly understood. Here, we identify a transcription-associated histone modification in human cells, mono...

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Literature Corpus work
95738348-6eca-5f52-bc94-2bcffd314b79
DOI
10.64898/2026.06.22.733675
Open publication

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H3K37me1 couples transcription with DNA replication origin selectionDOI 10.64898/2026.06.22.733675
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